Obviously Hashirama wins. Base Hashirama is already on par w/ Madara in speed and Madara is fast enough to pressure SM Naruto. SM just amplifies that. So in no way, shape or form will they be overwhelming him with their speed or whatever regardless of them starting from 10m away or 100m away.
Second of all Hashirama's techniques are wide scaled even outside of his large constructs and they all only require a single hand sign, including SS. Outside of PS Hashirama's base techniques are enough to pressure the Uchiha and give him the field advantage. So even if he weren't fast enough to create distance between him and the opposition a single clap of the hands and any jutsu he chooses creates the necessary distance.
Finally SS took on PS Kurama, which is >> Madara's PS>>Sasuke's PS>>>Itachi's Susanoo.
Mokujin, Mokuryu and SM enhanced Mokuton like Jukai Kotan and Hotei molest these 3 until PS is used by Sasuke and Madara, then SS comes out and turns these 3 into blood splats on the ground. Hashirama mid-high diff at the very worst.