To expand on a point I made earlier, Guy in the 7th Gate is quite capable of physically kicking through Sakura and Tsunade, especially when a
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. Madara would have been just as durable, if not more so, as Tsunade and Sakura at the time.
Whereas the only boost Lee had during that instance was Kyuubi chakra, and the only thing that it did for him (seeing he can't use ninjutsu) was provide a boost in speed/strength. That boost
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, but it did not put him at a level above Guy in the 7th Gate, not when simply opening the First Gate gives a x5 boost, and the latter Gates
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.
Then there's also the fact that Guy's feats in Base trump Lee's, as seen by both of their performances against Kisame, and by Guy's ability to avoid being warped by Obito. This gap in power simply widens with the Gates, as Guy's feats in the same Gate dwarf Lee's (seen in the 6th Gate with Asa Kujaku and him using it to evaporate a tidal-wave sized Suiton). Add the fact that he can open all at the time of the war arc while Lee can only open 6 and you can see Guy is clearly superior there as well.
Thus, Lee was capable of cutting through someone not less durable than Tsunade with a kick. The boost he received to do so only affected his strength/speed, and could not have been greater than the boosts he normally gets from the Gates. Even if it was, the gap between Lee and Guy is large enough that the Kyuubi cloak still could not have put him on the level of being fast or strong enough to pressure Juubidara. Thus 7th Gate Guy, who is much stronger than Lee was at that time, should be just as capable tearing through the duo with his attacks, especially when he has used kicks enhanced by the Gates before.
As for Katsuyu "tanking" Hirudora in an effort to protect Sakura and Tsunade, the only way that would be remotely possible is if they summon the slug and go inside it before 7th Gate Guy closes the distance. Which means they need to be faster than Juubidara and Sage Mode Minato. Seeing that they are nowhere near as fast as those two, Guy closes the distance, blitzes them both with a combo and eradicates them with a point blank Hirudora.