So...
1. Events occuring in Genjutsu realm are always possible in the first realm.
2. Sasuke was using Curse Mark when fighting with Itachi in terms of CQC.
3. Hachimon's first gate enhances your strength much more than Senjutsu Curse Mark.
4. Kakashi was fighting Itachi alone all the time.
5. Itachi in his third is as powerful as in his full strength.
6. Base Naruto from the start of Part II managed to surprise Itachi with a Rasengan while B and KCM Naruto didn't even land a hit on 2 vs. 1.
7. Itachi's intent was to kill these people.
If you can convince me on even 4 points, I'll agree with you.
2. If Sasuke was using CM1 and got overwhelmed by Itachi in CQC, then it would be a good assumption that they would be equal in CQC if he was in CM2.
3. 1st gate and CM1 are not stronger than the other.
4. Naruto was pretty irrelevant considering how he wasn't with Kakashi at the time. "But Itachi still had to look out for," Doesn't matter.
5. He had 20% chakra. Everything else was the same. His Taijutsu skills, his smarts and analytical skills. He didn't lose out on Ninjutsu.
6. When did Bee and Naruto fight Itachi 2v1? As far as I know, Nagato was with him. Also, the ten seconds of fighting they did, and didn't land a hit on him, doesn't really count.
7. Who specifically is he trying to kill?