I disagree with all the previous posts that say killing Madara is impossible for Sasuke.
There's something we are not taking into account: Sasuke's new powers are that: NEW so he is not experienced in using them, he just needs time to get used to them, and to get used not to rely on the cursed seal which he doesn't have any more.
Also, there's a chance both Naruto and Sasuke will confront him together in the end, Naruto has reasons to kill Madara, remember Minato told him "the guy with the mask" was controlling the fox. Some time in the future Sasuke will have been able to measure and study Madara's powers to make a plan to fight against him.