So Kakashi ran into Tobi many times before the big reveal and he never was under the suspicion that it could be Obito?
Kakashi clearly has the ability to distinguish people's chakra (he knew the big explosion was from Deidara immediately when they were searching for Sasuke).
How come Kakashi never sensed that Tobi was in fact Obito?
I guess when he was a kid he wasn't able to sense chakra as good?
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This (mangekyou awakening = hatred) + hashirama cells = i would imagine a complete change of his chakra signature
Kakashi's "reality" = dead Obito.Uchiha Itachi said:"People live their lives bound by what they accept as correct and true. That's how they define 'reality'."