In a straight on fight, Kakashi could take on Sasuke and start beating him mid-high diff.
However, once Sasuke starts losing, if he brings out Manda or CM, that will give Sasuke the ultimate win.
Teamwork with Naruto and Sakura though can allow Kakashi to possibly pull out the win against Sasuke assuming
Oro and Kabuto stay put. However, Manda will stay play a huge problem that Gamabunta won't be able to
fix completely.
Thus, it would go extreme-high diff either way. But yeah, I don't see Sasuke, without using CM or summonings, ever beating
Kakashi by himself at that point.