Nope. Hidan is retarded and sasuke is a genius. It would all come down to brains. Hell shikamaru a genius kicked his butt. Even if sasuke didn't know he would have learned how to beat him like he did with deidara.
Hidan can beat anyone aslong as he gets a drop of their blood but if Sasuke uses his Susano'o for defence then uses Amatersu to burn him down he could win
Hidan's obnoxious personality when fighting has him "play with his food." This is demonstrated by how he attacks parts of the body with his ritual that will not kill his opponent but hinder their fighting[
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]. He also shows this by the way he feeds of their sorrow in battle[
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]. Hidan in attempt to "play with his food" would cause him to reveal the secrets of his abilities in a match-up with Sasuke and Sasuke has shown to gain if not a full analyze an extremely accurate hypothesis[
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][
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][
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]. Sasuke would decipher Hidans abilities easily. Another factor is who's to say Hidan will even obtain the drop of blood he needs. Sasuke has Kenjustu feats on a much more grand stage than Hidan and with Sasuke's Lighting affinity his swift sword play would not be guarded against[
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]. Sasuke has shown to leave his Opponents alive but motionless with his blade alone[
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][
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]. Sasuke would defeat Hidan rather easily without Kakuzu to reattach his parts.