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Kabuto is the closest thing, but i mean hell he fought a monster who genetically modified himself to hell. I would of liked to see Itachi in a fight he was trying to kill Jiraya(Leaf Loyalty), Kakashi(Leaf Loyalty), Deidara(1 Shot), Orochimaru(1 Shot X2), Kabuto(Closest Thing), Sasuke(Didn't try to Kill).