I hope not, i just want the war to end.
And after all the the villains with Sharingan, Rinnegans and Juubis i don't see how can Orochimaru top the danger they posed at this point and possessing Sasuke's body is out of question right now (unless Kishi comes up with another great idea).
I want him to either turn good (after Kishi explains us why he turned against Konoha and show us he wasn't bad from the start) or leave everyone to continue with his experiments (implying he'll try something in the future), but being the final villain, hell no.