Naruto x Hinata it was obvious from the beginning, Hinata always blushed and liked Naruto, but even more than an obsession type thing, she admired his ability to never give up and her feelings for him pushed her to not only try harder but succeed in the end, she became the head of the main branch instead of Hanabi. Naruto began to show his feelings, in a way, by getting really upset when Neji nearly killed Hinata and wanting to beat him later in the final Chunin exam, he again shows it later during the Pain arch.
Sasuke was never interested in anyone, through out the manga. He lacked having anything that even resembled a crush on anyone or even attraction... he was so consumed by his ambitions. And suddenly he is with Sakura. I just can't imagine how those 2 would be. I would love to know how Sasuke shows his affection for Sakura or the dynamics of the relationship.
Sasuke I would have thought to be paired off with someone he hadn't met yet, that way we could see how the relationship and his feelings for her develop. Or something that would show more of Sasuke actually liking Sakura in the beginning, because nothing showed it, to make it look like he felt more for her than, she's just annoying and in the way. And suddenly out of the blue, he's in love with her, but it never showed before.
I actually expected Sasuke to be alone or develop feelings for another character who Kishimoto would introduce after Sasuke is no longer curse of hatred, and Itachi to be brought back to life (Samsara heavenly life, for whatever the reason), Sakura to cure his disease and him to continue the clan with Sakura. Sakura beginning to understand Itachi, she loses her childish obsession on Sasuke and develops a true affection and admiration for Itachi, his ideals and the genius he was.
It's kinda fanfic, but I actually expected something more like that, it would have made more sense to me because Sakura's crush on Sasuke wasn't genuine, it was just obsessive, and not a true love or admiration, and Sasuke just didn't have anyone who could bring out those feelings in him, was how it looked to me, which is why I would assume he'd be paired with someone new.
To sum it up, Sasuke's affection wasn't there for anyone, so I'd assume him paired with someone new, Sakura's affection was childish with nothing I could call close to love, she paired with someone similar to Sasuke because he's her type but her feelings were just obsessive
Anko x Kakashi
Sakura x Itachi
Tenten x Neji (if he didn't die)
Guy x Mei
Indra x Hitomi O
Karin x Jugo would be interesting to see
.... hmmmmm
Danzo x a cactus Danzo like a wood pecker to the cactus lol