Oonoiki is too old, he will die soon. so will Tsunade, she is the last of the sanin and will probs over use her medical thing and die. Sasuke will also eventually die. Kakashi could over exert himself and gai could go 8 gates and die too. Kabuto and tobi will have to be stopped too eventually. And who knows what happened to Anko and Yamato? Dead or what?