I agree with your list but am unsure about Killer Bee.
Hashirama would be based on hype. His best weapon against Nagato that he has shown would be his Flower Tree World. If Nagato happens to breathe in the pollen, he would become drowzy which could affect his performance or even sleep. Against the six paths of pain, I don't think they would fall asleep if they don't breathe. Ofcourse, the drawbacks would include seperate paths so if one gets disposed of, the path will be gone. Animal Path and Naraka Path will have to be riding the bird while the other paths and summons do the work so that it would give Hashirama a hard time to focus on them but ofcourse, there's Mokuton clones.
If Animal and Naraka are high enough in the air, if the paths die in battle, Animal Path could summon the corpse or remains and have Naraka Path revive the fallen path. Against Hashi's technique to cover the area in darkness, Nagato would have better chances since he's a sensor but the paths would have problems locating Hashirama so Hashi's best weapon against the six paths would be his Darkness technique(feel free to name it since I forgot the name).
If CT is used, then this would prove to be a huge problem for Hashirama. Others have said that he could prevent being pulled towards CT by restraining himself with his Mokuton but I don't see that happening when the entire ground itself is being pulled towards it.
So yes, with what has been shown, I believe he is capable of holding his own and perhaps even manage to defeat Nagato but CT is Hashi's biggest problem when facing him which could even mean Hashirama's death.
Killer Bee:
Killer Bee has shown massive techs but apparently all seemed to be chakra based(Hachibi). Preta Path and Deva Path would give him problems.
Against Nagato, Preta Path will be a pain to deal with along with CT or a Massive ST. The other ones for distractions or Animal Path for movement. The chameleon to gain invisibility or the bird to fly around with. The cerberus and the rest as the distraction which could also provide linked vision. If an opening is made, Human Path would be deadly.
Against Pein/Pain, the weakness her is that the 6 paths are in different bodies so if you get rid of one, the path is gone(unless Naraka Path lives to ressurect the fallen path) which could mean that if Killer Bee manages to take down Preta Path, it would give him a huge advantage. Meaning now he can use his chakra based techniques without feeding his own chakra to Nagato. The strength is that they feel no pain (when faced with genjutsu) along with having linked vision and 6 different angles to attack from (overwhelming his opponents). With the 6 paths of pain, Naraka Path serves a better purpose than with Nagato alone by reviving fallen paths.
What makes this not too one-sided would be Killer Bee's HURRICANE SPIN thing. Which could "bee" troublesome for the paths and even manage to get rid of a few of them (which could include Preta Path and Naraka Path).
Though I'm curious to see what would happen if Nagato uses Bansho Tennin on his opponent's eyes.