That depends on the shinobi offspring. Great genes doesn't necessarily a great ninja make. Look at Karin, Hinata, etc.
It's really Kishi's fault for not exploring the backstory of Hamura and his descendants during the manga. He did a rush job tying the Uzumaki and Senju clans together, but we know little about them. The Uchiha got all the attention.
because he was irrelevant to the plot
Or Kishi d*ck rode the Uchiha too hard. Literally everything is tied to them and everything is their fault.
Moon Eye Plan = Uchiha plot
Kaguya + Chakra Fruit + 10 Tails = Uchiha plot
Akatsuki = Uchiha plot
Kyubi Attack on Konoha = Uchiha plot
4th Great Ninja War = Uchiha plot
Naruto Gaiden = Uchiha plot. Because Shin was a big Itachi fap, despite never knowing him.
Sauske's entire journey in the manga = Uchiha plot. Even in Gaiden, when Sasuke is in his 30s, he's still talking about Itachi.
i combined your entire post into : Black zetsu plot :lol
Oh my gawd. That out of left field retcon to justify everything was hella dumb. It made Madara, Obito, Nagato and every other villain sans Orochimaru, look like a punk.
tbh, Kishi could've made blackzetsu into an actually evil and darker mind than childish behaviour. The way he act makes the entire Uchiha clan become a joke who fall into his silly trap...