it took madara till old age to unlock it with a PURE Senju dna.. sooo i doubt an Uzumaki dna would be good. But maybe its not dependent on the dna, butttt the eyes.
The mystery lives on cause if Nagoto had Madara eyes when did Madara give it to him and why did he have to technically reawaken the rinnagan, confuse what was Madara timeline like when did he meet obito to give him his eyes and who's eyes did Madara have when he met obito.