Look no Uchiha keeps His eyes active 24/7 at Home unless their under attack the same goes for Hyuga. The eyes is activated in combat,also its bad ethics to keep it active in day to day dealings unless you want people to be afraid of you using genjutsu against innocent people.
sasuke and itachi's mom was not born uchiha.... she married into the family....which is why the dad has sharingan and not her. thats like saying hyuuga males dont have byukugan because naruto does not have one
For all people saying that Mikoto wasn't an Uchiha... she was. :|
In Japan, even if you marry your first cousin (marriage between cousins in general), it's not considered incest.
She's not inbred in the manner that we don't even know how closely related Mikoto and Fugaku were. The Uchiha clan was so large (it's been around for years, since before the foundation of Konoha) that people within the clan would be barely related anyway, since years of generations have past. Even Itachi was supposed to have an arranged marriage with some Uchiha girl so that the clan could continue and his child would have been the heir after him.
For all the people saying females were shown with sharingan... only one was and it was in a panel where "Madara" was describing the Uchiha clan's conflict with the Senju. She was towards the bottom of the panel. Bottom right-hand corner, actually:
Nothing to do with her gender, I just felt that Salada might not get the sharingan or if she does it wont develop into MS or Rinnnegan whatever because its usually linked to your emotions and if you go through turmoil or the strive to become stronger. Unless Sakura and Sasuke die and Bolt completely rejects her, I dont know if she will have enough drive to awaken it.
Also with Sasuke away a lot I think it would be more likely for sakura to pass on her healing techniques to her. And you cant be a healer and in the front lines otherwise who will heal you if you get injured?