I think it is probably 50/50 after what she has shown recently, all she has to do is let him land a hit on her and grab any part of him she can and he's done for. If Naruto doesn't try to engage in any taijutsu he might win.
exactly, if naruto does rasenshruiken first he wins (with what we know of tsunade's arsenal)...
for all we know she has something to dodge it/block it... oro blocked a tbb with the gates, and she's the one who's supposed to be able to dodge and block every attack ... but w.e complete conjecture
if he does any taijutsu with her, its over for him, that would be his mistake