The location,Starting distance,Knowlage and restriction is in Tsunade favor but Kakashi is smart ass so Kakashi mid to high dif
P.S. you are Defenetly fan of Tsunade.
Scenario is like...
1.Kakashi activates Hiden mist jutsu then He Makes Lighting Clone and lets it to tsunade when tsunade kills Clone she is binded and Kakashi makes Chidori to the cheast.
2.Kakashi Starts with jutsu arsenal he has and Keap up with tsunade speed cous of sharingun
Then use Wire strings-(are thin pieces of wires that are highly durable and can be used for a variety of purposes, such as rappelling, manipulating weapons, binding and restricting the movements of an opponent or setting traps).And stomps Tsunade
3.Use genjutsu sharingun or genjutsu used in kakashi and obito fight.
4.Use Hiden mist jutsu and then Silent kiling tech....