Tsunade vs Hanzo

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As stated by Chyoi or what her name is, Tsunade in the 2nd shinobi world war, the latter was capable of countering all of her poisons something impressed her. Tsunade being medical ninja and doctor knowing the functions of the body and its working cells allows her to counter all of Hanzo's poisons.

Most likely when the Sannin fought against him, Tsunade was countering his poisons since she was the best medical ninja at that time which was her prime.

Tsunade mid diff.
 
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Bantos

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Tsunade low diff. Even without immunity to the poison she wins. And I could say that she actually does have immunity to it since Tsunade, Jiraiya and Orochimaru did not get poisoned while fighting Hanzo.
 
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