if it were 1v1, I think both would get beat pretty badly. But if it's both of them vs the 2nd, then, hmmm, might be close. the second's water jutsu is ridiculous and for all of kakashi's stealth, I believe the 2nd Hokage knows how many people there are, how far, and where just by touching his finger to the ground. plus, if he got a chance to whip out edo tensei, no idea how good he is at that, but it might turn the tables. I say Kakashi and Gai, but it might be close.