Tobirama was the fastest Shinobi in Madara's time. But his FTG was underdeveloped. But if he have FTG V2 he can beat MS or EMS Madara before Madara can use PS.
I think Tobirama could have beaten MS Madara. But after he killed Izuna and Madara gained the EMS, madaras power and ability sky rocketed. Tobirama couldn't beat an EMS Madara without V2 FTG, and even then it's a less than 10% chance of victory