*cracks knuckles*
The debate of weather Sasuke can defeat Kabuto or not ends here
first off lets look at taijutsu shall we? whalst Kabuto is in DSM he has enhanced strength and sensory not to mention his surgical precision with chakra scalpel. Which even Tsunade noted as being highly impressive in her battle with Kabuto, then there is the fact that Kabuto has the healing capability's of Both Karin and Orochimaru leaving all physical attacks useless.
Then there is genjutsu because of Kabuto being able to fight blinded all genjutsu is rendered useless.
I am also seeing allot of of arguments weather Amaterasu could hit Kabuto or not I say it is possible but unlikely seeing as how easily Kabuto was able to avoid Sasuke's Susanoo arrow arguably his quickest attack.
Sasuke's fire based jutsu can be counter'd with Kabuto's water based jutsu, here you could count that as a draw. allthough Sasuke does have lightning based jutsu which can counter Kabuto's earth release which is a point to Sasuke.
as for the Susanoo there are 3 jutsu we know of in Kabuto's arsenal that could take care of it 1,white rage 2,organic manipulation(spikes could attack from underneath Susanoo to pearce Sasuke) and 3, Tayuya's genjutsu. All of these attacks leaving Sasuke wide open for a finishing blow.
I could add more to how/why Kabuto would defeat Sasuke without much difficulty but this should be more then enough proof.