Alright
First Ill Post Kakuzu On the Defensive
Meis Boil Release .. I will counter her strongest jutsu first ..
Boil release could be counter'd by kakuzu in multiple ways the first is kakuzu is underated in terms of his speed ..
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Shown when he went from lying on the ground to slaming kakashi through trees in the matter of seconds . Or when he Speed Blitzed Chouji (dont go saying anyone can blitz chouji

) Because even shikamaru couldnt see it coming .. His feats of dodging are also Shown .When he was able to dodge shadow Stitching Fairly easily. So i believe Dodging The boil release would be No Problem for kakuzu seeing how Karin Was Able To Dodge it .
If dodging the boil release fails . It hasnt shown that it could even melt kakuzu's Earth Spear which the data book says is as hard as diamond .. which if true means lava would not be able to melt it .. seeing as it most likely was an exageration .. it still hasnt shown feats for it being able to melt it ...
Meis Corrosive Acid
Meis Corrosive acid could be countered Fairly Easily With Kakuz's Massive Wind Style Jutsu. Rivaling a natural disaster could easily blow her mist away..
Meis Water Dragon. .
I have heard that meis Water Dragon was especially strong for one ... but i have found out recently that she uses the same jutsu as zabuza did so it is not Stronger then the average water Dragon. If Not Dodged .. Water<Earth So It would deffenently Not be able to Pierce his Earth Spear ... Or He could Just Simply Melt It
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Now To Put kakuzu on the offensive i will just put it into one Broad Summary
Offense
Unlike kakuzu mei has shown no particular feats of dodging . and Her only defensive Jutsu is Water Encampment Pillar Which If not Evaporated By Wind+Fire Culd Be Pierced By the Threads Of EARTH Grunge Fear She could not just simply Dodge Due to their Quickness
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Before She Could Even use the jutsu She would Be in the process of being bombarded by Different Jutsu . from different directions. While Having to avoid (which is hard) or tank 3 massive Jutsu ( Searing Migraine , False Darkness, And Pressure Damage..) I watch English Dubb
XD If i missed anything of mei's or a weakness of kakuzu's Destroy me with it lol ( try not to insult each other as well that always annoys me when people are rude during debates)