Theory /Question There might be some uchiha survivors

[Uchicha Macho]

It could be but where would they be and how wouldnt sasuke or them not wrekonize each other

sasuke was place in care by sarutobi.there could be soe of the children end up as ophran or end up in the street similar to nagato when he was child

 

[skoraxascended]

there may have been children who survived, who then lived in "state home" as in danzo's secret eye growing and then extraction basement

so no
dead as doornails
and weren't sasuke and Itachi the youngest anyway?