probably not, they might if they were all brothers(if madara was the older brother and izuna younger than madara, and itachi younger than izuna, and sasuke younger than itachi, and if sasuke and madara got ems, and then one of them took the others eyes, then i think they would fuse, and make a super ems....but i dont think it could happen, unless sasuke is a direct decendant of madara.