Highly doubtful. I never say impossible anymore, because Kishi is always full of surprises. However, bringing back the Sage's son(s) just wouldn't make any sense.
No that will not be the case.....
I don't want another Madara stunt to happen because being so much powerful he spent most of his life in hiding as coward and using Hashirama's DNA to get rinnegan which can used when he is revived later on after already dying once......