Nope, anime and manga as a booming industry is here to stay, it will go out of business just as fast as the video game industry will go (as in never in our lifetime). Toonami was jumped started back in 2012 and hasn't looked back ever since, growing each and every month in ratings, services such as Crunchyroll and Funimation grow more prosperous with each passing quarter, and anime in general is still becoming more popular thanks to the help of the internet and social media. Anime is a big industry, one that won't die due to the ending of one ongoing series.