Sterling Malory Archer
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Itachi Uchiha, a main antagonist of the series Naruto Shippuden, dies of tuberculosis when fighting his younger brother Sasuke Uchiha. It is said he had had it since he first appeared in Naruto.
Peacemaker Kurogane character Okita Soji has tuberculosis, as did the historical man of whom this character is a fictional portrayal.
The same goes for the Bakumatsu Kikansetsu Irohanihoheto character Okita Soji who is shown in the last stages of his illness.
The anime Gintama also features Okita Sougo who is based on Okita Soji but here it is his sister, Okita Mitsuba who suffers and ultimately dies from tuberculosis.
Bleach character Jushiro Ukitake, the sickly 13th division captain is another anime character with tuberculosis. This one 100% fictional, it comes off as a moe-istic feature to make the character more attractive and likable through frailness.
Tsubasa: Reservoir Chronicle character Kurogane's mother also suffered from tuberculosis and as a result of her failing health she was unable to protect the borders of her country from any invading monsters.
Takenaka Shigeharu, also known as Hanbei and based on the historical Japanese samurai, is shown in the anime second season of Sengoku Basara: Samurai Kings as suffering from tuberculosis, a weakness that ultimately leads to his death at the end of the series although it is not clear which disease the historical character actually suffered from.
The Shimabara Arc of Rurouni Kenshin features Magdalia Sayo, who has tuberculosis (described as "consumption"), perhaps obtained from her mother, weakened from the same illness. Her illness is the only illness her brother Shogo Amakusa, trained in Western medicine, was unable to cure. Kenshin's teenage rival Okita Soji, a fictionalized counterpart of the historical First Division Captain of the Shinsengumi, was shown to have been suffering from this illness (by coughing blood) during a flashback in the first chapter of the Kyoto Arc; said illness was the reason why the two never actually battled one-on-one in hand-to-hand combat (Third Division Captain and fellow historical figure Hajime Saito confronted Kenshin in Okita's place instead) despite being acclaimed as the two strongest swordsmen active during the Bakumatsu era.
In the manga Blade of the Immortal the most talented fighter in the series, Makie Otono-Tachibana also suffers from tuberculosis.
So is TB an Anime or Manga thing?
