I am not sure if even the Totsuka Blade would be able to Seal a fully evolved Juubi, regardless of the fact that it has been known to have an ability to seal anything it touches.
I think... if there were One thing to break that rule it would be the Juubi, and the Juubi alone; seeing as all Jutsus, Chakra Manipulation, Division of Yin and Yang etc came from the Juubi.
HOWEVER as we know Rikudo Sennin was known to use Powerful Seals, and also Sealing Weapons in his battle against the Juubi. More recently Obito Sealed/Merged with(?) the Juubi. The Juubi does seem to be vulnerable against Sealing Techs so it's possible Totsuka Sword could do damage, however it is not one of the Sages Original Weapons so i think the Juubi could Counter it. (Visualise the Kyuubi and Narutos Chakra Tug of War).