Hashirama is also an exception
Take out Hashirama, all senju are fodder without kekkei genkai. Take out the top 5 uchiha, even then you will get more Uchiha with ability to awaken sharingan
Anyway, 5 uchiha > 2 senju
Uchiha wins
Naruto has no KKG and he's surpassed Sasuke.
Tsunade has no KKG and she traded blows and took a lot of physical punishment from with Edo (infinite chakra) EMS Madara.
Tobirama has no KKG and he solo'ed Izuna. He later went on to become the Hokage.
Kushina's chakra chains subdued a sharingan possessed Kybui. This after Kushina just gave birth.
Nagato was able to manipulate, animate and coordinate 6 different bodies using multiple jutus when he invaded Konoha. The senju's powerful bodies and powerful physical energy at work.
While not a combat ninja, Karin's sensing and healing abilities are first class.
So no, the Senju are not fodder. They all have to work hard for the power and control they attain. Each Uchiha who gets a sharingan gets wrapped up in the "power" of their eyes and thinks they can take on the world. Take the sharingan away from an Uchiha and compare them to a ninja of equal level and you'll be shocked at the result.