Naruto, low diff lol. Seriously, Orochimaru is inferior. This shouldn't even be questionable. Jiraya's Sage art: massive ransengan can hollow out a mountain, since Jiraya was an imperfect sage and Naruto's a true one, it's likely that his is even stronger. Naruto could easily take out any of Orochimaru's snakes. Remember how he destroying Pain's summons? Manda is not a threat. Orochimaru himself is not much of a threat given Naruto's superior reflexes. Ransenshuriken would destroy him. It destroys each cell. This means Orochimaru's regeneration is not a factor. It will hit him, I don't know why people think it's slow lol. At the very least, he can throw it in close quarters which Naruto stated is impossible to miss.