I played as a thief. I did some calculations, saw how many skill points I needed to level all the relevant perks for me. I finally found a near perfect build with Illusion, Sneak, Enchanting, Alchemy, Blacksmithing, Archery and Restoration. (+ some perks in One Handed and light armor).
Ended up needing 80 perk points.
I'm around level 64 now, haven't played in weeks
I crafted the strongest light armor and weapon in game with the strongest enchants. And I got full illusion, so I just run around one shotting everything. It's not so much fun anymore

Just use an illusion skill to have all the mobs in a large area start attacking each other.
Also, for your question. Pretty sure you cannot get all perks without the usage of console commands or mods.
There are 251 perks. Max level is 81. It is impossible to get higher level than that, thus no more perks.
There are some extra perks you can get through quest that dont require perk points like:
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