1) ok
2) i can't see totsuka blade not piercing sasuke susanoo (because its not a solid sword , its spiritual so it will move freely inside of him)
it doesn't matter where sasuke amaterasu the susanoo as long as there is not point to break him and the flames won't get to itachi
and about keeping susanoo , you are obviously talking about the sick itachi who fought sasuke did you see how much he kept it where he had so much chakra and i said that EMS sasuke > sick itachi
he has more powerful long range attack that will help him when the susanoo won't move freely
izanami can be used ,and so is KA
1) totsuka blade is a spiritual weapon existing in a physical form,itachi used it to cut oro's hydra heads didnt he?,oro was also looking for the sword as well,why would he be looking for it if he couldnt hold it?. Yata mirror is also a spiritual weapon,but sasuke used his sword to hit it as well as his explosive kunais as well,ans it blocked the attacks physically didnt it?.
2) the OP only said itachi wasnt edo,so i assumed he meant the nornal itachi,we have no ides how much chakra a healthy one has,kimimaro had a chronic sickness,but his chakra wasnt low was it?,oro's body was weakened,yet he did his kawarimi multiple times which a healthy could do only once.
3) Itachi pushed himself beyond his limits because he wanted to die at sasuke's hands and wanted to push sasuke to force oro out of his body,he wanted to die,which is why he used susanoo that long as well as his other ms jutsus. He was healthier in part 1,yet turned off his sharingan completely after one small ama and 2 tsukiyomis. When he was in the susanoo,he was coughing and the susanoo began to dissapear,but he still reformed it again,he purpsoely used it so that he would die. Sasuke can use enton on the ground around itachi,even if itachi is in his susanoo,he has to walk towards sasuke,and he will walk on the ground wont he?,if he sees it,he wont move forward,sasuke can make his ring of black flames around itachi and his susanoo,or just block the front,as he has the ems,his ama is stronger than an ms one,susanoo arrows have no affinity,except ama,which isnt weak to any affinity and burns through almost anything,so ama arrows continously will keep itachi at bay,enton flames on the grund will keep itachi from getting closer,not to mention the gact that the flames can create a good time for kirin. All the while itachi's stamna and body is getting weaker faster than sasuke.
4) Izanami?,do you know how long that jutsu takes?,itachi used his ms jutsus far longer than he would have even if he were healthy,his eyes would have given way. Once you do an ms jutsu you instantly begin to feel pain,your chakra reduces and your eyes bleed,healthy or not,that weakness is gone from the ems which only drains your chakra ems,which means sasuke will use his much longer than itachi can. That tech takes far too long,especially if itachi is going up against sasuke.
5) KA is in a crow,it has to fly and make eye contact,sasuke will simply ama the crow easily.