Sasuke: Looked up to his brother, and wanted him to acknowledge him, but Itachi usually ignored him, due to the tension of the village and the Uchiha. When the time came to destroy the Uchiha, Itachi made sure that no one harmed Sasuke. Sasuke hated Itachi afterwards, but was spared his life.
Trunks: Trunks lost everything he ever cared for, besides his mother Bulma. He watched as his own world was used as a playground for destruction, and had no means of stopping any of it. He even witnessed his own master and greatest friend, Gohan, get destroyed. He could only be destroyed by the Androids or go back in time and try to change the future.
Take it how you will.