Do you think Sasuke will use Izanami on Madara? I think it would work because Madara thinks that Hashirama's power is his power. He thinks of himself as a a god. However, if he lost Hashi's chakra, I think that would be a major power loss for him. At that point the Kage could take him. So do you think this is a possibility?
I highly doubt it, Madara called Hashirama's healing power Hashirama's
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, he didn't claim it as his own. He knows who he is, his name alone put fear into the world which started the war. He fully know who he is unlike Kabuto who tried to define himself by adding others to himself
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. Itachi even told Kabuto that it's fine if he wants to imitate a being he respects but he can't become one with that being
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.
Madara doesn't want to become Hashirama, he said when two opposing force work together, meaning Uchiha and Senju
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. Wanting to become like the Sage power wise is what Itachi told Kabuto was ok when he said imitating a being you respect. Madara isn't trying to become who the Sage is, not trying to define himself with the power so Izanami isn't going to work on Madara plus Madara knows about it and Itachi said it's not a jutsu to be used in real combat so Sasuke would die if he tried it and if he somehow cast it then Madara would just break out since he knows the jutsu and Sasuke will lose Amaterasu/Enton and Susanoo.