Ok seriously, I'm all for making sure people don't underrate Sakura but I don't think she can take Itachi.
Let's go down the list.
Can she tank anything he can do to her with normal jutsu, taijutsu, or weapons? Yes. Point to Sakura.
yeah but probably not for long
Can she hide from him the the forest and use stealth better than Itachi? No, Itachi was a genius ANBU operative who managed to kill his whole clan without anyone noticing until after the fact. Point to Itachi.
Can Itachi just see her hiding spot with sharingan? No, that's not how it works. He has the sharingan no the byakugan, unless shes in line of sight he cant see shit that way. Point to noone, it's irrelevant because she isn't superior to Itachi in stealth anyway.
itachi can use a couple of clones to scour with sharingan without her noticing , then dispel themselves and inform the original
Can Sakura recognize and dispel any of Itachi's basic genjutsu? Yes, she has extreme chakra control and has demonstrated the ability to break genjutsu as high as A rank even when she was a genin. Point to Sakura.
even if she knows itachi's genjutsus , she would most likely need to be aware of that in order to break one (unless you're suggesting that she constantly tries to disrupt her own chakra , which may hinder her chakra enhaced strength) .
itachi's genjutsu can be so subtle that she wouldn't notice anything's wrong
Can Sakura break Tsukiyomi with her yin seal? No, we have no evidence that that's the case. Point to Itachi.
Can Sakura beat Itachi's Susanoo? No, she can't she'll be lucky if she doesn't get sealed by the sword the first time she tries and get's blocked by the yata mirror. Point to Itachi.
Can Sakura deal with Amaterasu? Debatable, it's been shown to burn slowley and as a medic she should theoretically be able to cut off her skin that has the fire and then heal it up but it's never been shown so point to noone.
the pain from a full-body amaterasu would probably halt her for a while , meanwhile totsuka gg
Can Sakura land a clean hit on Itachi? Not likely, he's a sharingan master who was able to snatch sasuke's chidori casually out of the air by the wrist and Sakura hasn't been shown with any speed feats higher than the average jounin. Point to Itachi.
punching the ground creates debris/impact which may make dodging a bit more difficult
Summon battle? It's a wash with neither being particularly effective against each other.
doubt that. summoning is one of sakura's most offence in her arsenal . not to mention katsuyu's immense size (depends on how much chakra sakura wishes to spend)
Overall, Sakura can't really damage itachi, and itachi can't do any real damage to sakura unless he goes full on mangekyou spam on her... but if he does then she can't win. If he catches her eyes its over, if she comes anywhere near him she gets sealed.
It's not like itachi could just casually walk up to her and kill her anytime he wants without her being able to walk away, but sakura can't really take him down even if she wanted to.
Since only itachi the only one in the match capable of taking the other one down at all, I have to say Itachi wins.