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It is impossible for sasuke to ever rape Sakura, and not just because of her super strength.
THe manga suggest that if Sakura blitz Kaguya like she did Shin, she would'e solo'd her, Fortunatley for Kaguya Sakura aimed for her horn to knock her down.
And the fact Kaguya is not KO after that punch on the head unlike Shin
Head is most vurnerable and weaker compared to body plus brain is located there. Strong impact on the head will effect brain and can knock out or kill the person who got hit.
Medical 101 here