Maybe Sasuke has told her everything he's witnessed under Orochimaru's wing and also remember that her master is 1 of 2 people who's closest to Orochimaru.
He killed third hokage, attacked the village, tried to kill tsunade, took away sasuke. Idk why would any of them like oro? Naruto doesn't. he is just putting up with him so they can defeat shin. You can see the disdain for oro in this very chapter.
Whats not to like about Orochimaru but maybe it has something more to do with sarada and sasuke and karin I think maybe sarada is also just an experiment or clone of some kind and she is upset at the way orochimaru treats lives like they are nothing just my theory on it.