Hashirama and Kushina would.
Who can survive Mabui's transport technique? (Besides Sakura obviously)
Suigetsu and karin.
You're right, Karin isn't a senju afterall. The reason why tsunade survived with little injury is because of her senju blood...No, if that was the case part 2 Sakura could too. Karin doesn't regenerate she recovers by biting herself, it's basically healing with your hands, and besides her body isn't strong enough