Imho no way.....Itachi has already defeated him twice. With and without arms......until Oro defeats Itachi....then he cannot. That's just my personal take on this.
The differences is that Itachi died while Orochimaru gained far greater power with Senju DNA and Edos (Hashirama, Tobirama, Hiruzen, and Minato and he can control 3 of them).
This was explained in the manta already, Oro stated as such. To my knowledge the only person to defeat itachi was sauske. Finally sharinngan.
Orochimaru said that before he got a Senju DNA made body and Edo Hokages.
no....explain how he is getting outta izanami or izanagi or how ever their spelled
Well for 1 thing, it wouldn't work on current Orochimaru who saw it worked on Kabuto and admitted he was wrong for trying to define himself with other people powers so if Itachi used Izanami then Oro would break out by knowing how it works and not being the same person as he was before. Plus Itachi said it's not a jutsu to be used in a real battle as we seen by Edo Itachi getting fatally wounded many times. Also you're assuming Itachi would get passed the Edo Hokages when Itachi still has his disease that would kill him if he push himself, all Hokages know how to fight a Sharingan user, MS side effect leaves Itachi open for attacks.
I know there was just a thread about this but I could handle all the logically flawed comments. Now I am a third year college student and a seven year Naruto fan, so it's safe to say that I have a little knowledge on this subject. I am here to prove on why Orochimaru would beat Itachi in a fight. Also I we be delivering my knowledge in systematic ways, instead of spewing out tons of information that most times leads to confusion and frustration.
There are may reasons why Orochimaru would be Itachi in a fight, but I will stick to the top there. First I will remind people that Orochimaru has very powerful edos at his disposal, and this should be a key factor when analyzing a fight between him and any person of Naruto verse. Next I will discuss his immunity to physically attacks. And finally I will give solutions to problematic situations that may occur when fight Itachi while also addressing his feats and hype.
Everyone often time forgets that Orochimaru has Edo Hokages at his disposal, three of which he can control freely. And lets not forget that the fourth Hokage has the nine tails within him. Now because of his most recent power up he has gain greater refine of his Edo jutsu this gives him the ability to control the Edo body more precisely and the ability to bring back the bodies at nearly full power. I mean this fight wouldn't merely be between Orochimeru and Itachi. It would be Itachi VS Orochimaru, the nine tails, and the four Hokage , that is a fight that Itachi just can't win.
Now I want to ask a simply question. How do you kill him? Raise your hand if you know the answer. How do you kill Orochimaru (Not seal him KILL him). Huh Huh!!! No Solid answer. Because no one knows, no physical attacks seems to work. He either vomits another body, or he acts like he is dead slowly gets up laughs and continues basically not phased. Lets just relapse on some of the futile attempts to kill Orochimaru, First off fire doesn't seem to work because if you remember Sasuke tried to burn his face off, and he just laughed it off. Then during that same arc Sasuke seemed to break his neck on a thick tree branch using a form of Hidden Lotus Taijutus, but again his efforts were to no avail. Lastly I'll fast forward to part two during Kabuto's memories, particularly the one in while Orochimaru introduces Kabuto to he lab and reveals leaf village's corruption. During this time Kabuto attacked Orochimaru by using his charka edged hand to repeatedly slash Orochimaru's throat. Now I believe that this incident is the most impressive, because here there was undeniable fatal damage to a vital part of Orochimaru's body, not only that but there was blood shed and he didn't retreat into a different body. These are just a few examples of his endurance in battle.
Lastly The T Blade is the most dangerous part of Itachi's arsenal and Itachi's has already defeated Orochimaru with this very technique and this could be the very reason why it would work a second time around. Orochimaru already knows that his has it and know to be wary of it. And we must remember that this guy has many feats including going head to head with the J man, the fifth, and a six tailed Naruto, all with no arms. There is a lot of thing that will do know about Orochimaru, but there is also a lot that we don't about Orochimaru. For example we had never seen orochimaru at his full power except in part one before he got his arms stolen, and now with this new found power his hype is on another level.
Due to his very powerful Edos at his disposal, his immunity to physically attacks, and his: knowledge, feats, and hype. Orochimaru would beat Itachi. (Note Please disregard the spelling and grammar errors. I didn't have the time nor effort to perform a proper revision.)
It was 4 tail version 2 Kurama not 6 tails, Pain fought 6 tails. Also Orochimaru had use of his arms, he was using ninjutsus such as the gates he summoned, spitting out dagger wielding snake army, and such. Oro gains his arms after switching bodies for a short time as shown when he used Edo Tensei. Also Oro was in better condition fighting Naruto than when Sasuke beat him, Naruto only further weakened Oro by his over use of oral rebirth.