I say Sasori.
I doubt Orochimaru would be able to concoct an anti venom of the multitude of Sakura's.
its just one, attack and he's a goner.
sure he has edo tensei but I'm sure He wouldnt even have the chance to use it, nor Do I think Oro would choose to use it right off the bat.
Sasori also has the Iron sand and puppet army. I believe he would simply overpower Oro.