Well the reason I was wondering is that Kimimaro can control the density of his bone,
and survive attacks by even gaara's sand. Now if he had full control of his powers and his curse seal, I don't really see what Orochimaru can do to kill him.
He survived gaara's sand by making a layer of super hard bone underneath his skin so that he couldn't be crushed, which makes me think that he couldn't be crushed by anything, and he was still able to move despite his skin above that layer of bone being cut up badly.
Most of the snake attacks we have seen Orochimaru use so far would just be cut to pieces while attacking, and the larger ones wouldn't be able to crush, eat or kill him.
The only way I can see Orochimaru winning is by trying to drown or suffocate him,
although since gaara kept him underground for ages, that probably won't work either.