Once again it seems that their paths will cross again. This time it will be about rescuing Sasuke. With Orochimaru having insider information on byakugo and him being somewhat of a sensei to Sasuke there is enough plot there to have another gaiden arc. I feel as if Oro will play a more significant role in the future. He has always been critical to the plot but mostly behind the scenes. Oh yeah and he also knows about curse marks and may have some idea of what the karma seal is.