Oro also has the
potential to do big things with
upgraded power.

I just can't picture him being defeated by 10 year olds without Naruto or Sasuke's help. Technically, he can still collect Naruto and Sasuke's blood from their fight at VoTE. :yeah: He managed to get that of all 4 Hokages, and Kabuto managed to get Madara's so nothing's impossible.
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He has a zetsu clone body (made from mokuton/gedo mazou) so technically he has the perfect body since it doesn't age, and with his knowledge on Hashirama's cells I'm sure can regenerate his body parts as well, he might have mokuton the same way Obito did.
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He doesn't need an Uchiha body.
All he's missing are Uchiha eyes, and guess what Obito left after his death.
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Kabuto is the only one who knows where it is, and after gaining Kabuto's knowledge when absorbing his power, Orochimaru also knows the location of Tobi's lair.
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As you can see Sasuke was already blind before and after the surgery and was re-located to a cave monitored by zetsus when he healed. I doubt he knows about the lab and if he does, he might have a harder time finding it compared to Orochimaru.
Also orochimaru has experience in combining sharingan with mokuton cells
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Also, this might be a stretch but since Orochimaru is a godly genius in bio-chemistry, could he find a way to tap into the Shinju's energy/chakra ? He could try and re-create a chakra fruit o.o
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