Re: the 5th Hokage is gonna DIE
Her goal came clear when she was introduced to the manga. Her goal is to make sure Naruto succeed to become the Hokage, because she wants Dan and Nawaki's dream to succeed through Naruto, since she put her life on line one last time, to finally, for once, see that the one she cares for, will successfully achieve his dream. Then she will finally have peace with Dan and Nawaki.
I highly doubt she will die before that happens. She will entitle Naruto herself I believe. And we will have a flashback of Tsunades past of Nawaki and Dan, thinking something like "We finally did it, Dan, Nawaki".