Orochimaru and Taka ain't gonna do any difference here, son. Sasuke also clearly stated his desire to get rid of the Bijuu, so that's just irrelevant.
Getting rid of the bijuus is impossible as they'll just be revived, he ment to seal them.
Hell if there's no bijuu then momo won't even get chakra from bee in the first place.
And Momoshiki and Kinshiki got rekt by an exhausted Naruto who had his chakradrained and a nerfed Sasuke from dimensional travel, and were later rekt again by a rasengan that shouldn't even be TBB bomb level by 12 year old with zero experience and an even more exhausted adult Sasuke.
Orochimaru has edo tensei, and infinite options, Jugo can make Sasuke even more powerful with his senjutsu , Karin keeps Sasuke's healthy and can even support with her chakra chains that were able to destroy SS arms which rekt Madara's Kurama PS.
Kin and Momo are nothing tbh, even adult Sasuke and Naruto should beat the individually if Naruto just uses clone feints and crush his rinnegan like a far inferior boruto did and then nuke their asses, and Sasuke can straight up ameno his sword through momo's rinnegan like he did to Madara and proceeds to rape them with his PS chidori.