Hashirama terribly Loses. Nagato cuts his brayn and tears off his schull. With Jigokudo he rips out his Throad Soul and tears of his Donsils voice Soul. Then uses Asura to kill him off easily. Easy win for Nagato.
No. Thats not the Point. Big ST Plus BT combined can collide and shatter SS with the collision or Nagato touches it and rips out its yang energy away. Nagato can also Utilizes ST to trip SS. Once it falls Nagato can Speedblitz towards hashirama can catch him and absorb his soul and Chakra simultaneously as he has shown.