Muu is a beast no arguments there. but so is itachi.
and I'd give the edge to itachi,
remember, muu may have amazing powers, but in the he lost to madara, who was also a MS user (EMS though) even though he had onoki along with him. and plus madara wasn't even scratched
check this out;
onoki and muu stand against madara
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the same place, check the dojo-alike thing and the stairs. onoki is down, muu is nowhere to be found but madara doesn't even have dust on his clothes
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EMS madara was most likely stronger than current itachi, but still, after what madara did this to muu and onoki at the same time, do you actually think itachi cannot take muu down in a 1 vs. 1?
this not good a flying ninga can do a bad worse thing to one in ground lets talk about sasuke vs deidara sasuke closely managed to defeat deidara because hes flying low .when he flys far high that is about 800m or something and using flying paper bombs what we seen in shippuden 262 its difficult to avoid likewise one with using flying+invisibilty gave him high advantage when using simultaneously but in reality uchia fans not recognize this like i said a no 1 player can be defeated by 10 by shocking
-Jinton can be a problem for Itachi, like we saw with Onoki and Madara. But it takes more than one tech to beat an opponent. Itachi being as fast as he is and as smart as he is can formulate a plan to just simply catch Mu in a genjutsu even if it is at the cost of losing his eye sight
What? Sharingan can see chakra thus probably Muu when he is invisible, unless Kishimoto told us he couldn't be sensed but I think not. Otherwise Yata Mirror for Jinton and Totsuka Sword.
"Mū is capable of becoming perfectly camouflaged with the surrounding environment. His camouflage is so good that he has become renowned as the "Non-Person" (無人, Mujin), a title which he gained for seemingly having neither form nor chakra, while the technique was active.[6] It is impossible to detect him by normal means and so, Mū considers anyone with the ability to sense his presence worthy of praise.[7]"
Saw this on narutopedia. Would sharingan be able to detect this? If not it would be hard for itachi to beat him, no? All that said I still think itachi wins.
We have to remember Kages are like S-class shinobi who will die for their village, akatsuki are S-class shinobi that are fed up with the lies in the shinobi or another reason. Not saying you thought Mū was stronger because he was a Kage, I was just clearing this up.