Most suffering characters?

[TenseiganFTW]

What is your list?
My list is:
1.Zeref(Suffering from immortality).
2.Zone(Yugioh 5ds)his world got destroyed by card games.
3.Itachi(Suffered from hiv/aids)
4.Sanji(Suffered from transgenders).
5.Obito(Got his balls crushed by that giant stone,lost his dream,lost his GF)

 

[BLAZE]

Toneri
Fodder villian who Got oneshotted by KCM naruto's punch

 

[Kamui Sama]

the answer is Guts

 

[NineSNS]

Indra and Ashura - so bad they couldn't even let it go after death

 

[Kingu]

Madara, he got fisted by a black sperm.