I take it that by 3 tomoe Obito, you're referring to Obito as he was before his Mangekyō was revealed, yes?
Once Hashirama performs his Moku Bunshin technique, he and Obito will be at an advantage. It would seem that only an Eternal Mangekyō Sharingan user can see through this Jutsu [
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], and as such, the likelihood of Kakashi being successful in landing a fatal Kamui shot is reduced drastically. The Moku Bunshin is one of those Jutsu which remains menacing even with full knowledge for the opponent, because you'll never be able to distinguish between the ever durable clones and the original. We also have to wonder how effective Kakashi would be in trying to warp a large area or group of clones, since we know that Obito is capable of cancelling Kakashi's technique if he's fast enough in reacting to it, as we've already seen once before [
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].
Shodai has an incredible amount of experience fighting with the Uchiha and their ocular powers. He will not fall to Tsukuyomi, particularly with full knowledge. Since Obito can casually see through any illusions with his sharingan, it'd be pointless for Itachi to even attempt any form of Genjutsu on him. The former will also be free to alert the 1st to any Genjutsu he may be caught in. From what we've seen, Obito was able to handle Minato's Hiraishin up to v1, only being caught out by v2 because of a lack of knowledge and by being relatively inexperienced. Any member of team Kakashi could be finished by Obito's near instant warp, particularly if explodes from the ground to lay a hand on them. The only reason that Naruto wasn't lolstomped by such a tactic was because of his ability to sense negative emotions [
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][
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]. Neither Itachi, Minato or Kakashi possess any of the required sensing abilities which
may've improved their chances of reacting in such a circumstance, although Obito's chakra can't be sensed when his body is in his pocket dimension anyway. The risk of being defeated like so is very high considering the three of them would also be engaged with multiple Mokuton doppelgangers; they won't even be able to give their full attention to looking out for Obito. None of them can exhaust Obito's five minute intangibility, and the three of them, if engaged by Hashirama's techniques aswell, won't be able to overcome him easily in CQC. Let's remember that Obito, with nothing more than the Gunbai and Kamui, was able to easily troll the combined efforts of Naruto, Kakashi, Gai and Bee [
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][
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].
With Hashirama's large scale Wood Release, Minato's kunai (and any subsequent seals which may've placed in the environment) will be effortlessly displaced [
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]. He won't be able to arrange a set of markings which he could use to bamboozle either Obito or Shodai, and will be limited to v2 Hiraishin (which would eventually run out). No-one on the initial team has the kind of firepower needed to annihilate these kind of Jutsu. Not even Amaterasu, which taxes Itachi heavily, would be enough to trouble Shodai, who can easily regrow his forests or simply eliminate the black flames from the equation [
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]. Hashirama can have some clones merge with the trees and provide intel regarding his opponents via telepathy [
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][
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]. Summons can either be crushed with Jukai Kōtan [
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], quelled by the Mokuryū [
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] or slaughtered with Mokuton Sashiki from the master of Wood Release [
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]. Minato's Hiraishin isn't quick enough the allow him to escape a bloodlusted warp [
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][
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]. The manga has also implied that the only way in or out of that dimension is through the use of Kamui.
Kakashi and Itachi's stamina/chakra reserves leave alot to be desired. Hashirama and his team mate's are among the best in the manga. If the situation calls, Obito can always resort to using the complete Izanagi to pick off anyone who lets their guard down, even for an instant. Hashirama can continue creating Moku Bunshins and hounding his opponents with the Wood Style. If any of them are restrained by Shodai's Wood Release, their chakra can be absorbed as happened to Kisame. What'll happen if the 1st's Bringer of Darkness Genjutsu is used? They'll be pretty much finished. You must grab your opponent to end it, but how'll that happen when both Obito and Hashirama are able to freely move into the ground? Random Mokuton spikes erupting from the floor will effortlessly bypass Itachi's Susano'o and kill him. It would be too easy for Obito, unaffected by the technique, to move in and warp his now blind opponents.
Hashirama and Obito, 10/10.