Itachi's Tsukiyomi is unbreakable.
Itachi was lying in part one, the same kakashi who experienced tsukuyomi first hand said it can kill him easily. If that's so, are uchiha members suddenly break such a lethal thing just because they have blood? Are uzumakis immune to death reaper just because they have splendid lifeforce? That makes zero sense.
Black zetsu called itachi's genjutsu the strongest.
Kakashi stated no one can break Mangekyou Sharingan genjutsu let alone Tsukuyomi.
This blood + sharingan/MS is bullshit, how can you break a genjutsu in which the person can control space( can suffocate you to death, can cancel all space to crush your body), time(torture you infinitely by turning the clock to infinite minutes), matter(Can control the atoms and molecules in your body, crushing it in the realm, the same thing, the sensation of being crushed and disintegrated will be felt in the real world which the enemies cannot tolerate and bear).
Literally unbreakable, just time passage alone will distort your sense of time to even attempt breaking it.
Are uchihas suddenly immune to oxygen lack, atomic disintegration, no space to exist in that world.
No they are not, and Itachi's words are contradicted by part 2 kakashi and Tobi who said Sasuke didnt break it. Despite having indra's spirit and cursed seal in him to allow him.